Episode 07: How can patients be safely withdrawn from their psychiatric drugs

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Training Psychiatrist and Clinical Research Fellow in the UK National Health Service, Mark Horowitz, has published guidance about how to withdraw safely from psychiatric drugs. In this episode, Peter C Gøtzsche interviews Mark Horowitz who gives practical advice about how to taper the drugs in a hyperbolic fashion. He also recounts his personal experience of horrific withdrawal symptoms when he tried to withdraw a depression drug and did not know how to do it.

Documentation:

Horowitz MA, Taylor D. Tapering of SSRI treatment to mitigate withdrawal symptoms. Lancet Psychiatry 2019;6:538-46 (behind a paywall).

Horowitz M, Taylor DM.The Maudsley Deprescribing Guidelines: Antidepressants, Benzodiazepines, Gabapentinoids and Z-drugs (The Maudsley Prescribing Guidelines Series) 2024.

Gøtzsche PC. Mental health survival kit and withdrawal from psychiatric drugs. Ann Arbor: L H Press; 2022.

Gøtzsche PC. Withdrawing from psychiatric drugs: How to produce smaller doses than those the drug companies provide. Mad in America 2023; Nov 21.

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